Looking around the world and in Taiwan, the number of patients suffering from vertigo is increasing year by year When faced with vertigo testing, most people will choose to have it diagnosed by a doctor or hospitalized with neuromedical imaging tools such as MRI or CT for interpretation However, this may lead to misdiagnosis of vertigo, overdiagnosis of patients, waste of medical resources, etc, and cannot be effectively traced back The actual condition of the patient's dizziness In order to solve the long-term clinical pain point of vertigo, Neurobit has developed a smart wearable medical device - NeuroSpeed smart glasses and an AI assistance system It provides an AI smart solution for rapid screening of vertigo, assisting doctors in quickly screening more than 80 of brain diseases Efficient detection power with accuracy and sensitivity of over 90 Neuron Technology was founded in 2016 The co-founders include Yang Juncheng, Chen Weicheng, Huang Jinxun and Wang Jingfu The four of them were studying at the National Taiwan University Medical Engineering Institute and the Creative Entrepreneurship Program to jointly offer the "Biomedical Innovation and Commercialization" course Next, let’s embark on the entrepreneurial journey together The core team members of Neuron Technology are mainly composed of cross-field experts in medical engineering, information technology, neurology, patents, business, etc The common entrepreneurial concept is to continuously explore and explore unsolved pain points in medical clinical practice Seeing that patients were suffering from vertigo, Neuron Technology invented and independently developed an efficient and practical wearable smart medical device, NeuroSpeed Smart Glasses, which combines hardware AI-assisted decision-making system software to provide an AI smart solution for rapid dizziness screening Neuron Technology CEO Yang Juncheng said that the proportion of people in Taiwan and the world who suffer from vertigo is very high In Taiwan, as many as 3 of the people about 700,000 suffer from vertigo, while in the United States, about 1,000 people suffer from vertigo Tens of thousands of people go to see a doctor due to vertigo From the data, it can be seen that the vertigo medical care market is quite huge Regarding rapid screening for vertigo diagnosis in the clinic, current rapid screening tools in hospitals mainly use neurological examinations, and most of them are processed through questionnaire-type scales The diagnosis will rely too much on the patient's chief complaint and the doctor's experience judgment, and lacks quantitative indicators, resulting in Misdiagnosis of vertigo and loss of golden treatment time For patients with vertigo who are admitted to the emergency department, medical diagnosis in the past relied heavily on neuromedical imaging tools such as computed tomography CT or magnetic resonance imaging MRI After observation, it was found that the equipment was insufficient In the United States, the number of patients admitted to the emergency department Less than 3 of the population can receive immediate MRI diagnosis, and less than 50 can receive CT diagnosis However, excessive use of CT or MRI diagnosis may lead to overdiagnosis and treatment of patients, and even waste of medical resources In order to help vertigo patients accurately and efficiently screen and triage and reduce over-diagnosis in clinics and emergency rooms, NeuroSpeed Smart Glasses, a wearable smart medical device developed by Neuron Technology, is believed to have a great impact on the overall application of medical resources and patient diagnosis and treatment It is very helpful Yang Juncheng said that if it is not necessary to use MRI to track the diagnosis, this device can be used as a rapid screening test before the existing MRI neuroimaging tools and after the patient is admitted to the hospital, reducing over-diagnosis of patients NeuroSpeed's examination method is to quickly screen for nystagmus to identify patients with potential brain diseases The examination method of this technology is to observe the trembling state of the eyes and a series of eye movements when the subject is staring at a stationary object, so as to judge Brain risks for appropriate diagnosis and treatment NeuroSPeed smart glasses can crack brain and eye diseases, clinical trial sensitivity reaches 90 With the active research and development of Neuron Technology, two generations of NeuroSpeed smart glasses have been successfully launched The first generation NeuroSpeed mainly provides doctors with real-time observation of high-quality eye images and eye movement response-related examination data reference, and does not provide auxiliary diagnosis services The second generation of NeuroSpeed allows physicians to record, track, store and view relevant eye movement analysis and pupil area identification, thereby effectively diagnosing diseases of the central, meridian and peripheral nervous systems Because the second-generation NeuroSpeed product has the function of assisting doctors in analysis and diagnosis, it has been classified as a Class II medical device in the United States and must be certified by the US FDA before it can be sold externally At this stage, this product has completed pre-submission and will be submitted for review after the biocompatibility test is completed It is expected that the second generation NeuroSpeed will successfully obtain US FDA certification next year In terms of actual verification fields, NeuroSpeed has currently cooperated with New Taipei Shuanghe Hospital and Taichung Tzu Chi Hospital for clinical verification Its clinical results have confirmed the classification judgment of central nervous system diseases such as stroke and other vestibular system diseases With the addition of NeuroSpeed Smart glasses are designed to be lightweight and easy to carry, detect quickly and easily, and have the functional characteristics of automatic interpretation They can effectively assist doctors in quickly screening for potential brain disease risks in patients with vertigo Field verification with foreign medical centers mainly involves vertigo patients admitted to the emergency department Physicians can use NeuroSpeed smart devices to interpret the phenomenon of stroke diagnosis Currently, the accuracy of clinical trials in the above-mentioned cooperative hospitals reaches 80 and the sensitivity reaches 90 Neuron Technology develops smart wearable medical device NeuroSpeed smart glasses In addition to becoming the best smart medical assistant for doctors to quickly screen brain disease risks in the clinic and emergency department, NeuroSpeed smart glasses also assist doctors in the detection and assessment of strabismus risk They are jointly developed with the Tri-Service General Hospital through neuron technology The "Portable Strabismus and Abnormal Eye Movement Diagnosis System" is implemented in the Tri-Service General Hospital, providing doctors with a complete preoperative assessment of strabismus and postoperative tracking basis This excellent RD technology achievement was recognized by the 17th National Innovation Award-Clinical Innovation Award in 2020 We know that many diseases can cause congenital or acquired eye movement abnormalities, and even cause symptoms of strabismus or nystagmus Among them, as for strabismus, according to expert physician consultation surveys, the global prevalence of strabismus among school-age children is 2 5, while the prevalence of strabismus among school-age children in Taiwan is about 1 to 4 Yang Juncheng said that clinical diagnosis of the symptoms of these diseases is mainly divided into two categories deviation measurement of eye position and eye movement test It has been observed that there is currently a lack of objective quantitative methods for diagnosing eyeball position deviation, and eyeball deviation measuring instruments are used to check subjectively For Neuron Technology, the current NeuroSpeed instrument and strabismus and abnormal eye movement diagnosis system software can integrate objective and clear eyeball images, eye muscle function and eye deviation angle data as a rapid test that meets clinical diagnostic criteria Service, the data of these tests can be used as the basis for doctors’ complete preoperative assessment and postoperative tracking of strabismus Therefore, this system can provide objective and effective quantitative analysis, which can greatly reduce the medical risks of patients during surgery In terms of business model, Neuron Technology mainly cooperates with hospitals to sell research-based products It is believed that the company expects to have significant revenue performance after passing the FDA next year At present, Neuron Technology will use the country's first wearable smart medical device NeuroSpeed smart glasses and AI assistance system to provide software and hardware integrated solutions to assist doctors in quickly screening brain diseases and eye diseases, extending patients' golden treatment time and reducing social risks health care costs to create a triple win NeuroSpeed smart glasses assist doctors in quickly screening brain and eye diseases Looking at the world, the pioneer of smart medical equipment, a new paradigm of biomedical software and hardware system integration In the early days of Neuron Technology’s entrepreneurship, technology research and development and business expansion faced many challenges Yang Juncheng expressed his sentiments that since the NeuroSpeed product is the first medical smart glasses developed in China, both in terms of obtaining hardware raw materials and developing technical specifications, The challenges associated with building and integrating related systems are higher than those for consumer electronics Additionally, bringing together cross-disciplinary talent and integrating it into a core team is also an entrepreneurial challenge In terms of business development, although the company has accumulated clinical verification results and published related outputs, the establishment of market channels still requires continuous efforts to expand It is hoped that it can continue to rely on the assistance of legal persons such as the Capital Strategy Council to actively create more diversified market channels and connect potential Cooperating manufacturers In order to accelerate international expansion and market operation exchanges, the company will conduct a new round of fundraising planning at this stage to meet development Since its establishment, Neuron Technology has taken long-term development and stable profits as its operating goals Yang Juncheng said that in addition to focusing on existing professional fields, we also develop and apply value-added products through the company's software development and software development The accumulated RD energy of hard integration is expanded to other medical disciplines and fields Yang Juncheng hopes that Neuron Technology can become a pioneer in smart medical equipment, with research and development oriented to meet the needs of users and patients, and also hopes to become a model for the integration of biomedical software and hardware systems For the medium and long-term layout, the company will promote industry-university exchanges and cultivate biomedical talents integrate upstream and downstream industry resources to create smart medical solutions and platforms and actively explore foreign sales markets such as the United States and Europe as a basis for sustainable development of the company Vision 「Translated content is generated by ChatGPT and is for reference only Translation date：2024-05-19」

With the advent of the post-epidemic era, the development of global telemedicine is in the ascendant, which has greatly increased the demand for smart medical technology in decentralized medicine Among them, if mobile medical devices can provide real-world at home or outside the hospital data for use in hospitals, it is believed that it will reduce the burden of diagnosis and treatment on doctors or medical personnel and reduce health insurance expenses To this end, Singular Wings Medical has launched a comprehensive telemedicine solution, which combines excellent wearable mobile medical device design, innovative software development, AI algorithms and cloud platform services, and will become the last piece of telemedicine puzzle David Lee, the founder and general manager of Qiyi Medical Electronics, said that his original intention to start the business was because he witnessed Taiwan's long-term pursuit of low-cost mass production, which led to the continuous decline in the value of the industry For example, in the past thirty years, The output value of the former Silicon Valley was similar to that of Taiwan's Hsinchu Science Park, but thirty years later, the output value of Silicon Valley reached US14 trillion at the end of 2020, while the output value of Hsinchu Science Park was less than NT15 trillion at the end of 2021 Seeing Silicon Valley's sensitivity to industry needs and disruptive innovations such as Uber, Airbnb, industry trends and the post-epidemic era have driven a surge in telemedicine services, thereby creating high industry value, so I started a business at the age of 45 and conceived how to combine it with Taiwan After more than ten years of accumulated industrial advantages and Silicon Valley's innovative model, we decided to help Taiwan's industry upgrade and find a new path through the integration of the medical industry, ICT technology industry and innovative business models Seeing that Taiwan has always been a gathering place for the most elite talents in the medical industry and electronics and electrical industry, I believe that through the combination of the two and innovative business models, we can have the opportunity to follow Silicon Valley and create a different business According to Taiwan’s Communication Diagnosis and Treatment Methods, Taiwan’s market demand for telemedicine is divided into two situations emergency such as COVID-19 and special necessity such as special geographical locations such as outlying islands or mountains It is allowed Carry out communication medical diagnosis In fact, the development of global telemedicine decentralized medicine is in the ascendant, but the demand for smart medical technology to meet decentralized medicine still needs to be realized In addition to the medical technology gap, it also includes medical treatment flow, patient identification, remote Remote consultation and collection are fueling the push for smart medical technology Li Weizhong observed that for telemedicine decentralized medicine to be successfully implemented, it is best to use telemedicine devices that are used outside the hospital or at home and are easily available in daily life Among them, the data of the device is the key It can provide doctors with out-of-hospital real-world data Real World Data or Real World Evidence that they can trust and apply, so that they can improve their diagnosis and treatment methods In fact, this type of telemedicine device is not popular, making remote medical care difficult to complete In addition, as the number of wearable devices such as bracelets and watches increases, most of the data that these devices can truly provide is insufficient for medical purposes and is not easy to validate and verify Li Weizhong said that people are paying more and more attention to health awareness, which is a positive encouragement for telemedicine devices He believes that as long as there is an appropriate business model and the right way to cooperate with hospitals and doctors can reduce the burden on doctors or medical personnel and reduce health insurance expenditures, Qi Yi Medical Electronics will definitely have the opportunity to become the last piece of the puzzle in telemedicine Founded in 2015, Qiyi Medical Electronics’ core team consists of 22 diversified professionals, including young engineers with medical, engineering and information backgrounds and experienced entrepreneurs, working together to create an overall solution for remote healthcare The solution includes hardware design, software development and backend cloud platform services for the mobile medical device Beatinfor Health electrocardiogram sensor Electrocardiogram ECG is one of the most important vital signs body temperature, pulse, respiration and physiological data of the human body, which can reflect various physiological changes in the human body, such as cardiovascular health, inflammation, infection, bleeding, injury or anxiety index changes For this core concept, Qiyi Medical is committed to using wearable electrocardiograms as its core technology, while collecting important vital signs and environmental parameters such as electrocardiograms, and building AI algorithm systems and backend cloud platform services based on big data and machine learning to help solve remote problems Specific chronic diseases such as cardiovascular disease, sleep problems, and metabolic diseases are the most important in medical treatment Electrocardiogram sensor continuous physiological data monitoring reduces the risk of death in acute heart failure patients by 11 within 30 days after discharge In order to realize remote medical services, Qiyi Medical Electronics has launched a complete set of remote medical care solutions, including wearable mobile medical devices-electrocardiogram sensor BEATINFO ECG, BEATINFO HEALTH APP, and AI algorithms , web pages and BEATINFO HEALTH cloud service platform The BEATINFO ECG sensor is an exclusive device for the BEATINFO HEALTH APP health cloud platform It can be used continuously for 40 hours when fully charged The device is only 15g This sensor can collect the user's electrocardiogram, respiration, and skin temperature through a patch or chest strap , body movements, postures and environmental parameters Currently, BEATINFO ECG sensor has 8 patents in the United States and Taiwan, and won 2 German iF Design Awards in 2017 Mobile medical device-electrocardiogram sensor can provide continuous physiological data monitoring In terms of overall technical features, the BEATINFO HEALTH cloud service platform has four key physiological data detection characteristics continuity, long-range, real-time and dynamic In terms of operation, users can download the BEATINFO HEALTH APP on Android or iOS systems Its interface can provide physiological data status, order health assessment reports such as one-day sleep assessment report or cardiovascular health assessment report, and high-intensity exercise test Cardiovascular assessment reports, third-party remote medical consultation services and other functions Users use patch-type or chest-strap ECG sensors paired with end-to-cloud platforms for continuous physiological detection Before being transmitted to the cloud for further calculations, all data will be de-identified and made available to professionals Data reports are provided for physician judgment The BEATINFO HEALTH cloud service platform has powerful noise filtering processing capabilities, fast waveform recognition and judgment, as well as highly complex cloud architecture and communication technology Why is the noise filter processing capability so important Because medical equipment in general hospitals must require users to complete short-term measurements under static conditions Usually, data in life situations outside the hospital cannot be collected by the hospital, and this data is very important to doctors It is increasingly important to understand the progression of the disease and the condition of patients leaving the hospital Therefore, if we continue to record very weak ECG signals in daily life, we actually need to overcome a very high technical threshold After these signals are processed by the noise, they will first be judged by the AI algorithm before preliminary and rapid conclusions can be made Users can instantly avoid certain fatal risks The cloud architecture provides a deeper level of second-order computing and also covers the business model architecture It provides service models such as user management, automatic report generation, record keeping, alarm notifications, and connection with more services such as third-party alarms Emergency rescue, third-party medical consultation, doctor and patient docking, medical treatment cash flow and other functions In terms of competitive advantages in the industry, compared with the industry's braceletwatch products, Qiyi Medical's electrocardiogram sensor BEATINFO ECG provides accurate medical-level measurements, and can continuously record and collect physiological data, improving any Sudden or sporadic symptoms may occur Compared with the electrocardiogram patch of its peers, it provides real-time data return and web-based management tools, and can produce various reports for managers to remotely manage a large number of users on the web According to statistics from Beijing Medical University, the mortality rate of patients with acute heart failure within 30 days after discharge is as high as 11 If an electrocardiogram sensor is installed on the patient for continuous and real-time monitoring for 30 days, it is possible to reduce part of the risk of death, and at the same time, it can Significantly reduce health insurance costs Additionally, in the case of cardiovascular disease, if the user wears the device for a period of time, regular cardiovascular assessment reports can be obtained and provided for follow-up in-depth examinations by doctors In addition to the measurement of cardiovascular diseases, the ECG sensor configuration can provide home assessment of sleep apnea OSA During the measurement, patients can discover potential and easily overlooked cardiovascular diseases, and users do not need to stay in the sleep ward for treatment After a boring night, through the ECG sensor patch and AI algorithm, patients only need to sleep at home for one night to receive an OSA test report If needed, doctors can access patient status remotely and instantly via any internet browser Therefore, through the ECG sensor wearable service, users can discover hidden and unknown cardiovascular diseases such as arrhythmias related to sudden death from the measurement process to avoid unnecessary regrets Qiyi Medical Electronics’ business model is mainly B2B2C, hoping to assist individuals, hospitals, enterprises, care services and other units to create a win-win situation Li Weizhong analyzed that the business cooperation model is quite flexible, whether it is leasing or buying out wearable measurement devices, or providing annual report subscriptions to reduce the cost of purchasing devices for users, such as including 2-minute electrocardiogram, Flexible subscription package including 7-day cardiovascular health assessment, exercise cardiovascular health assessment, sleep health assessment report, etc Group cardiovascular monitoring system solution creates a many-to-many real-time physiological information monitoring platform to replace diagnosis with prevention In addition to providing individual users with remote mobile physiological data measurement, the BEATINFO cloud platform provides a "group cardiovascular monitoring system" solution that can create many-to-many real-time physiological information monitoring through network technology Based on the platform, patients only need to wear a lightweight monitoring patch, and the back-end system can grasp the changes in their physiological information, so that prevention can replace diagnosis and reduce the chance of sudden cardiovascular death This platform provides 3 functions, including the ability to manage different users into groups and hierarchically, and the number of users can reach tens of thousands it can display users’ basic physiological information in real time on web tools, and can be used under certain preset conditions When triggered, this platform will immediately send out an alarm historical data can also be reviewed on the platform, which is very suitable for doctors to check the patient's disease progression outside the hospital during consultation For the application of the "Group Cardiovascular Monitoring System" solution, taking high-intensity exercise as an example, such as long-distance running and cycling, mountain climbing activities or traveling abroad, a prior cardiovascular health assessment is required activities, and corresponding evaluation reports This report allows users to share it with doctors, so that participants can make assessments before the event or test their training effectiveness, which can significantly reduce the risk of accidents during the event beforehand During the activity, the group cardiovascular monitoring system also provides real-time on-site monitoring of a large number of participants It can be monitored in real time by the AI in the background at the moment of exercise Once an accident occurs, the platform can immediately issue an alarm and even report the accident GPS positioning of the location, and continuously transmits back the user's physiological information during search and rescue, striving for golden rescue time In sports monitoring applications, taking golf as an example, how to improve golfers' puttinghitting performance A player's performance and concentration are usually directly related to personal emotional stability Li Weizhong said that through HRV analysis of Qiyi Medical's electrocardiogram device, it can help determine the player's emotional and stress index performance, and at the same time help golf coaches select and train players The group cardiovascular monitoring system can create a many-to-many real-time physiological information monitoring platform Establish a firm foothold in Taiwan, move towards the US and European markets, and move towards the goal of a data company Faced with the challenges of technology research and development and market promotion, Qiyi Medical Electronics’ automatic identification of electrocardiograms requires a large amount of data for AI calculation development For this reason, Qiyi Medical Electronics must cooperate with hospitals and develop jointly Finish At present, the company has established good cooperative relations with many medical centers and research units, and has overcome these technical bottlenecks one by one In terms of market promotion, Li Weizhong said that the biggest challenge facing Qiyi Medical Electronics is to communicate with the market and let the public understand the differences between competitors' bracelet and watch products and the company's mobile device-electrocardiogram sensor Compared with the common bracelet and watch products on the market that collect electrocardiogram data in a discontinuous manner, it may take a long time to collect discontinuous data before potential cardiovascular problems can be discovered by luck Qiyi Medical Electronics actively promotes electrocardiogram to the public in a continuous manner The competitive functional characteristics of sexual detection data and emphasize that it is a very important means to assist in the detection of many potential diseases, replacing diagnosis with prevention and reducing the occurrence of unnecessary cardiovascular diseases In addition, in terms of business promotion, we also hope to create more opportunities for business matching and new venture capital raising with the assistance of the Corporate Resource Strategy Council Looking to the future, Li Wei and Xu Qiyi Medical Electric Energy will become the last piece of the telemedicine puzzle in the health wearable device-electrocardiogram service Li Weizhong said that in the short term, Qiyi Medical hopes to gain a firm foothold in Taiwan and become a common medical device in everyone's home, just like thermometers and blood pressure monitors The company is also constantly developing new indications Starting from electrocardiogram, coupled with AI and big data, it can deal with more chronic diseases In addition to cardiovascular diseases, we have also successively developed sleep apnea and other more special diseases The applications are aimed at the problems of elderly chronic diseases that modern people are very likely to encounter With a mid- to long-term plan, Qiyi Medical will enter the US and EU markets, become an international company, and continue to aim to become a data company, making good use of the company's long-term collection of data applications to provide services in diverse fields such as new drug development and vaccine development application to create business opportunities and profits 「Translated content is generated by ChatGPT and is for reference only Translation date：2024-05-19」